Cabergoline for men & women: Dostinex (Know Your Medicine)

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. There are some much rarer side-effects of cabergoline. Very rare cases of heart valve damage have been reported. Usually your doctor will listen to your heart before starting cabergoline treatment, and they may arrange an echocardiogram heart scan. This scan may be repeated if you need long-term treatment. It is very unusual for cabergoline to cause clinically significant heart problems, but you should alert your doctor if you developed shortness of breath or ankle swelling. If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist. Serious side effects You may find that any side effects you experience are strongest at the beginning of your treatment. However, they should subside or disappear as your body adjusts to the drug (Allen 2014a,b). Taking your medication with meals, or just after a meal, may help, particularly if you feel nauseous after you take your tablets (Allen 2014a,b).

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When your baby breastfeeds, or you pump your breast milk, the nerves in your breasts send a signal to your brain to release the hormones; oxytocin and prolactin. The prolactin tells the milk glands in your breasts to make more breast milk, and the oxytocin is responsible for getting the breast milk from your breasts to your baby. This is why it can be dangerous to still consume Cabergoline when you fall pregnant, as if you do not have that high level spike of prolactin within the body, you may not start to produce any breast milk. Depending on your prolactinoma, your symptoms and your situation, you may need no treatment at all, or there may be alternatives such as oestrogen or testosterone treatment. If you are not able to tolerate treatment with cabergoline, or if it is not effective in your case, there are similar medications that can be considered, or other treatment options including pituitary surgery. Your endocrinologist will discuss the options with you. Other information

Cabergoline is used to treat hyperprolactinemia (high levels of prolactin in your body). This happens when your pituitary gland makes extra prolactin. High prolactin levels may be caused by a hormone problem or by a tumor in your pituitary gland.

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HFEA. 2015. Getting started: your guide to fertility treatment. Human Fertilisation & Embryology Authority. www.hfea.gov.uk Opens a new window [Accessed October 2016]Once you become pregnant, the Cabergoline medication must be stopped, as although the lower levels of prolactin within the body will help to start the process of ovulation, after you achieve your goal of becoming pregnant and your baby is born, prolactin actually helps to start the production of breast milk. Cabergoline works well to help you ovulate regularly, and it's thought to be as safe as bromocriptine to take (Glezer and Bronstein 2014). Although the usual recommendation is to stop cabergoline at least a month before trying to conceive, your doctor will advise if and when you should stop taking it (BNF 2016).