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BNF for Children 2021-2022: September 2021-22

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Vaccines update: restructure of monograph content—creation of two class monographs, Vaccines, general (information common to all vaccines) and Vaccines, live (information relevant to live vaccines only); see examples in yellow fever vaccine or hepatitis A vaccine. a b c d e "BNF Publications - Books". www.bnf.org. BMJ Group and Royal Pharmaceutical Society. Archived from the original on 17 August 2016 . Retrieved 16 August 2016.

Adrenaline/epinephrine: recall of Emerade® 500 micrograms and Emerade® 300 micrograms auto-injectors, due to the potential for device failure [National Patient Safety Alert advice]. It is provided to NHS staff - usually through their employer, but may be accessed online through MedicinesComplete. [10] A new edition of the BNF book is published twice-yearly, in March and September. [1] The current edition is 85, which was published in March 2023. It is a tradition that the colour of each new edition is radically different from the previous. [2] Availability [ edit ] Vaccines update [classifications changed to Vaccines, live or Vaccines, inactivated and non-replicating]. The British National Formulary is divided into various sections; with the main sections on drugs and preparations being organised by body system.This update contains 11 significant changes, 7 dose changes, 1 classification change, 3 new monographs, and 1 new preparation. Azithromycin [update to dosing for uncomplicated non-gonococcal urethritis in children aged 12 to 17 years old].

Information on drugs is drawn from the manufacturers' product literature, medical and pharmaceutical literature, regulatory authorities and professional bodies. Advice is constructed from clinical literature, and reflects, as far as possible, an evaluation of the evidence from diverse sources. The BNF also takes account of authoritative national guidelines and emerging safety concerns. In addition, the Joint Formulary Committee takes advice on all therapeutic areas from advisers from expert groups; this ensures that the BNF's recommendations are relevant to practice. In September 2016, the National Institute for Health and Care Excellence (NICE) in the UK gave NICE accreditation to the processes to produce BNF publications; a further review in 2021 resulted in the successful renewal of accreditation. [3] History [ edit ] Janus kinase (JAK) inhibitors: new measures to reduce risks of major cardiovascular events, malignancy, venous thromboembolism, serious infections and increased mortality [MHRA/CHM advice] (advice in abrocitinib, tofacitinib, upadacitinib; see example in tofacitinib). Hyoscine hydrobromide patches (Scopoderm® 1.5 mg patch or Scopoderm® TTS patch): risk of anticholinergic side effects, including hyperthermia [MHRA/CHM advice].Controlled drugs and drug dependence: updated guidance on prescription requirements for Schedule 2 and 3 Controlled Drugs. Wade, O. L. (1993). "British National Formulary: Its birth, death, and rebirth". BMJ (Clinical Research Ed.). 306 (6884): 1051–1054. doi: 10.1136/bmj.306.6884.1051. PMC 1676980. PMID 8490505. The BNF for Children developed from the British National Formulary (BNF), which prior to 2005 had provided information on the treatment of children, with the doses largely determined by calculations based on the body weight of the child. Drugs that cause thromboembolism: pharmacodynamic effects drug group deleted from Appendix 1 interactions.

Cefotaxime [update to dosing for uncomplicated gonorrhoea, and update to include dosing in children from 12 years old for disseminated gonococcal infection]. Nitrofurantoin: reminder of the risks of pulmonary and hepatic adverse drug reactions [MHRA/CHM advice]. Ceftriaxone [update to include dosing in children from 12 years old for gonococcal conjunctivitis, gonococcal epididymo-orchitis, and disseminated gonococcal infection]. Tranexamic acid: new indications for haemorrhage following major trauma, and prevention and treatment of haemorrhage following head injury.VNRAS.com, BNF 73. "BNF 73" (PDF). Archived (PDF) from the original on 21 October 2021. {{ cite web}}: CS1 maint: numeric names: authors list ( link) Quinolones: reminder of the risk of disabling and potentially long-lasting or irreversible side effects [MHRA/CHM advice] (see example in ciprofloxacin).

Kendall, MJ (2009). "Chairman of the Joint Formulary Committee, British National Formulary". Clinical Medicine. 9 (4): 349–352. doi: 10.7861/clinmedicine.9-4-349. PMC 4952503. PMID 19728509.Vaccines update: restructure of Influenza vaccine monograph—creation of monographs for influenza vaccine (live) and influenza vaccine (inactivated). Many individuals and organisations contribute towards the preparation of the BNF. It is authored by Pharmaceutical Press, the Royal Pharmaceutical Society's (RPS) knowledge business; and is jointly published by the BMJ (owned by the BMA), and Pharmaceutical Press (owned by the RPS). It is published under the authority of a Joint Formulary Committee (JFC), [2] which comprises pharmacy, medical, nursing, and lay representatives; there are also representatives from the Medicines and Healthcare products Regulatory Agency (MHRA), the UK Health Departments, and a national guideline producer. Valproate: reminder of current Pregnancy Prevention Programme requirements; information on new safety measures to be introduced in the coming months [MHRA/CHM advice] (advice in sodium valproate, valproic acid; see example in sodium valproate). Anon (1957). "The British National Formulary". British Medical Journal. 2 (5047): 758–759. PMC 1962234. PMID 13460381. Non-steroidal anti-inflammatory drugs: potential risks following prolonged use after 20 weeks of pregnancy [MHRA/CHM advice].

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