Lattoferrina 200 Immuno 30 Stick Pack PromoPharma

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Carvalho CA, Sousa IP, Silva JL, Oliveira AC, Gonçalves RB, Gomes AM (March 2014). "Inhibition of Mayaro virus infection by bovine lactoferrin". Virology. 452–453: 297–302. doi: 10.1016/j.virol.2014.01.022. PMID 24606707.

Gao Y, Hou L, Lu C, et al. Enteral lactoferrin supplementation for preventing sepsis and necrotizing enterocolitis in preterm infants: A meta-analysis with trial sequential analysis of randomized Controlled Trials. Front Pharmacol. 2020 Aug 7;11:1186. View abstract. Andrés MT, Viejo-Diaz M, Pérez F, Fierro JF (April 2005). "Antibiotic tolerance induced by lactoferrin in clinical Pseudomonas aeruginosa isolates from cystic fibrosis patients". Antimicrobial Agents and Chemotherapy. 49 (4): 1613–6. doi: 10.1128/aac.49.4.1613-1616.2005. PMC 1068597. PMID 15793153.

Dobryk D, Dobryk O, Dobryanskyy D. The effect of enteral lactoferrin supplementation in prevention of morbidity associated with immature digestive tract in premature infants: prospective cohort study. Georgian Med News 2022;(323):94-101. View abstract. Motoki N, Mizuki M, Tsukahara T, et al. Effects of lactoferrin-fortified formula on acute gastrointestinal symptoms in children aged 12-32 months: A randomized, double-blind, placebo-controlled trial. Front Pediatr. 2020 May 19;8:233. View abstract.

Kuipers ME, de Vries HG, Eikelboom MC, Meijer DK, Swart PJ (November 1999). "Synergistic fungistatic effects of lactoferrin in combination with antifungal drugs against clinical Candida isolates". Antimicrobial Agents and Chemotherapy. 43 (11): 2635–41. doi: 10.1128/AAC.43.11.2635. PMC 89536. PMID 10543740. When applied to the skin: There isn't enough reliable information to know if lactoferrin is safe. It might cause skin irritation. Zhao X, Zhang X, Xu T, Luo J, Luo Y, An P. Comparative Effects between Oral Lactoferrin and Ferrous Sulfate Supplementation on Iron-Deficiency Anemia: A Comprehensive Review and Meta-Analysis of Clinical Trials. Nutrients 2022;14(3):543. View abstract. Jellin JM, Batz F, Hitchens K (2007). Natural Medicines Comprehensive Databas (10thed.). Therapeutic Research Faculty. p.915. ISBN 978-0-9788205-3-4.Drobni P, Naslund J, Evander M. Lactoferrin inhibits human papillomavirus binding and uptake in vitro. Antiviral Res 2004;64:63-8. View abstract. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Publisher's note Andrés MT, Fierro JF (October 2010). "Antimicrobial mechanism of action of transferrins: selective inhibition of H+-ATPase". Antimicrobial Agents and Chemotherapy. 54 (10): 4335–42. doi: 10.1128/AAC.01620-09. PMC 2944611. PMID 20625147. Lactoferrin and lactoferricin inhibit in vitro growth of Trichophyton mentagrophytes, which are responsible for several skin diseases such as ringworm. [62] Lactoferrin also acts against the Candida albicans – a diploid fungus (a form of yeast) that causes opportunistic oral and genital infections in humans. [63] [64] Fluconazole has long been used against Candida albicans, which resulted in emergence of strains resistant to this drug. However, a combination of lactoferrin with fluconazole can act against fluconazole-resistant strains of Candida albicans as well as other types of Candida: C. glabrata, C. krusei, C. parapsilosis and C. tropicalis. [63] Antifungal activity is observed for sequential incubation of Candida with lactoferrin and then with fluconazole, but not vice versa. The antifungal activity of lactoferricin exceeds that of lactoferrin. In particular, synthetic peptide 1–11 lactoferricin shows much greater activity against Candida albicans than native lactoferricin. [63]

a b c Bennett RM, Davis J (January 1982). "Lactoferrin interacts with deoxyribonucleic acid: a preferential reactivity with double-stranded DNA and dissociation of DNA-anti-DNA complexes". The Journal of Laboratory and Clinical Medicine. 99 (1): 127–38. PMID 6274982.Berthon BS, Williams LM, Williams EJ, Wood LG. Effect of Lactoferrin Supplementation on Inflammation, Immune Function, and Prevention of Respiratory Tract Infections in Humans: A Systematic Review and Meta-analysis. Adv Nutr 2022;13(5):1799-1819. View abstract.