ColdZyme Mouth & Throat Spray (Not Nasal Spray) - Cold Virus Treatment & Symptom Relief - Use at First Signs of a Cold - Menthol Flavour 20ml

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The study followed a previous single-blind trial investigating the use of two different scales to assess the common cold. This trial was conducted between January and April 2019, prior to the global outbreak of SARS-CoV-2 [registered at ClinicalTrials.

The incidence rates of TEAEs (treatment-emergent adverse events) in the ColdZyme group and the placebo group were comparable; 4. For categorical other secondary endpoints, χ2 tests, unstratified as well as stratified by study center (Cochran-Mantel-Haenszel test), were used for between-group comparison. Out of the participants who reported absence of a cold in the previous week, 69% reported a positive answer to the question if ColdZyme had prevented them from catching a cold in the previous week. The safety and tolerability of ColdZyme have been confirmed in a large study population and further establishes evidence of a faster recovery from common cold symptoms. The barrier reduces the ability of the virus to bind to the cells in the mucous membrane and cause illness.You can change your choices at any time by visiting Cookie preferences, as described in the Cookie notice. Finally, the trypsin enzymes (responsibly sourced from cod as a sustainable biproduct of the fishing industry) deactivates the virus particles, inhibiting them from infecting cells, multiplying and then spreading. The primary endpoint was defined as the AUC of WURSS-21 QoL composite sub-scores assessed during first 8 days of symptoms.

According to the International Olympic Committee Consensus Statement on Load in Sport and Risk of Illness it is estimated that about 50% of all acute illness in athletes during competitions and tournaments affect the respiratory tract [6] . Topical menthol is well-known to act on mucosal TRPM8 sensory receptors in the oropharyngeal cavity, perceived as cooling sensations that provide an increased sensation of nasal airflow, improve physiological performance, and give a sense of reward [ 27].of the reported colds were experienced as milder and/or shorter than usual and 69% of the participants who did not have a cold reported that they experienced that ColdZyme had prevented or might have prevented them from catching a cold in the previous week.

In addition, several safety endpoints were defined, including physical examination, vital signs and adverse events throughout the study, as well as global evaluation of tolerability by subjects and investigators at study end and assessment of device deficiencies at Visit 2 and Visit 3.ColdZyme Strawberry Anti Cold/Anti Flu Mouth Spray 20 ml Viruseptin Lozenges against Cold and Flu 20 pc. There are few approved products designed to intervene early in common upper respiratory viral infections involving the posterior oral-pharyngeal cavity. Lastly, the safety and tolerability of ColdZyme shown in previous trials [ 13, 14, 19] has now been confirmed in a large study population. ColdZyme ® Mouth Spray is a CE-marked medical device that works by creating a temporary, local, protective barrier on the surface of the mucous membrane in the oral cavity and throat. Based on the results of a previously conducted trial with the same investigational device in a comparable setting [ 14], n = 338 subjects (with n = 169 subjects per treatment group) was assessed as required for the primary confirmatory statistical analysis of the study.

Hemilä H, Fitzgerald JT, Petrus EJ, Prasad A, Zinc Acetate Lozenges May Improve the Recovery Rate of Common Cold Patients: An Individual Patient Data Meta-Analysis, Open Forum Infectious Diseases, Volume 4, Issue 2, Spring 2017. ColdZyme ® is intended to be used against colds during virus exposure and can shorten the cold if used early in the course of the disease. ColdZyme Mouth Spray makes it harder for the common cold virus to cause illness, and when used in the early stages of an infection it shortens the duration of the cold. Early self-diagnosis and early use of ColdZyme mouth spray is a safe alternative for treatment of naturally occurring colds.Protects: F orms a protective moisturising barrier on the mucous membrane of the oral cavity and throat. The barrier deactivates airborne viruses at the back of the throat - stopping them from sticking to cells and causing infection.