BENACORT® Nasal Spray – 24hr Hay Fever Relief – Alcohol Free – Fragrance Free – Budesonide Nasal Spray – 60 Sprays, 10ml

Product Information

Do not use more than two sprays into each nostril in a day. Do not use it continuously for more than 1 month. Cetirizine Tablets and Solution - over-the-counter, non-drowsy. For children and adults from 2 years. The metabolism of budesonide is primarily mediated by CYP3A enzymes. Co-treatment with CYP3A inhibitors, e.g. itraconazole, ketoconazole, clarithromycin, HIV protease inhibitors e.g. atazanavir, indinavir, nelfinavir, ritonavir and saquinavir, and cobicistat-containing products, are expected to increase the risk of systemic side effects (see section 4.4). Concomitant use of this product with HIV medicines is contraindicated (see section 4.3). The combination of this medicine with potent CYP3A inhibitors should be avoided unless the benefit outweighs the increased risk of systemic corticosteroid side effects, in which case patients should be monitored for systemic corticosteroid side effects. The interaction is of limited clinical importance for short-term (1-2 weeks) treatment with itraconazole or ketoconazole or other potent CYP3A inhibitors but should be taken into consideration during long-term treatment. If this medicine is co-administered with anti-fungals (such as itraconazole or ketoconazole), the period between treatments should be as long as possible. A reduction of the budesonide dose should be considered Results from prospective epidemiological studies and from worldwide post marketing experience indicate no increased risk for overall congenital malformations from the use of inhaled or intranasal budesonide during early pregnancy.

b. Holding the bottle upright, with one finger held on either side of the nozzle, the patient should insert the tip of the nozzle into one nostril. The nozzle should be directed to the side of the nose, and away from the middle of the nose (the nasal septum). The nozzle should be pressed down once or twice depending on the dose required. The spray should then be administered into the other nostril in the same way. Note: it is not necessary to inhale at the same time as spraying. After using your spray, wipe the nozzle with a clean tissue and replace the cap. How long to use it for Using the nasal spray twice a day: If you prefer, you can use one spray into each nostril every morning and evening. If your symptoms improve, reduce this to one spray into each nostril in the morning.Benacort won't relieve your hay fever straight away - you have to use it regularly for a few days for it to build up an effect.

Budesonide is excreted primarily as metabolites in the urine and faeces. No intact budesonide has been detected in the urine. Budesonide systemic clearance is 0.92 to 1.4 L/min. The half-life of unchanged budesonide following both inhalation and intravenous administration averages between 2 to 4 hours. Patients should consult a physician if they develop signs or symptoms of an infection, such as persistent fever, while taking this medicine. based on mechanistic plausibility and extrapolation from other budesonide/corticosteroid formulations.Budesonide is excreted in breast milk. At therapeutic doses of this medicine no effects on the breast-fed infant are anticipated since maternal systemic exposure after intranasal administration is low, so minimal exposure to intranasal budesonide in breast-fed infants is expected. This medicine may therefore be considered for use during breast feeding. Budesonide is a non-halogenated glucocorticosteroid with a high local anti-inflammatory action within the respiratory tract.

you have ever had a bad reaction to budesonide or any of the other ingredients of this medicine (listed in section 6) The nasal spray can take three to four days to build up its effect, so it won't relieve hay fever symptoms straight away. Ideally you want to start using it just before the pollen season starts to help prevent your allergy from developing. However you can also use it to relieve hay fever symptoms that have already started. Key facts about Benacort nasal spray Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes medicines that you buy without a prescription and herbal medicines. This is because Benacort® Hayfever Relief can affect the way some medicines work, and some medicines can have an effect on Benacort® Hayfever Relief. So, your doctor may wish to monitor you carefully. In particular talk to your doctor or pharmacist if:

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Try to remember to use budesonide spray regularly, even if your symptoms are controlled. If you forget a dose at your usual time, take it as soon as you remember unless your next dose is due. If your next dose is due then have the dose which is due and leave out the forgotten one. Do not 'double up' to make up for a missed dose. If you forget to use your spray, use it as soon as you remember, unless it's almost time for your next dose. If this happens, skip the missed dose and have your next one at the usual time. Concomitant treatment of seasonal allergic rhinitis may sometimes be necessary to counteract eye symptoms caused by the allergy. Maintenance treatment with inhaled budesonide (200 or 400 micrograms twice daily) in asthmatic nursing women results in negligible systemic exposure to budesonide in breast-fed infants. In a pharmacokinetic study, the estimated daily infant dose was 0.3% of the daily maternal dose for both dose levels, and the average plasma concentration in infants was estimated to be 1/600th of the concentrations observed in maternal plasma, assuming complete infant oral bioavailability. Budesonide concentrations in infant plasma samples were all less than the limit of quantification.

Before using this medicine for the first time the nozzle must be primed (filled with the medicine). To do this the bottle should be shaken and the protective cap removed. The bottle should then be held upright and the nozzle pumped up and down several times (5-10 times) spraying into the air, until an even mist is seen. The priming effect remains for approximately 24 hours. If a longer period of time passes before the next dose is taken, the nozzle must be loaded with medicine again. This time it is sufficient to spray just once into the air. If you prefer to use Benacort once a day, use two sprays into each nostril in the morning. Once your symptoms are under control you can reduce the dose to one spray in each nostril in the morning. If you're prescribed budesonide, your doctor may advise you to use it for longer. If you forget to use it Visual disturbance may be reported with systemic and topical corticosteroid use. If a patient presents with symptoms such as blurred vision or other visual disturbances, the patient should be considered for referral to an ophthalmologist for evaluation of possible causes which may include cataract, glaucoma or rare diseases such as central serous chorioretinopathy (CSCR) which have been reported after use of systemic and topical corticosteroids.You may not feel the medicine working for the first few days. It takes a few days to feel the full protective effect of this nasal spray, If you prefer to use Benacort twice a day, use one spray into each nostril in the morning and one spray into each nostril in the evening.