Dabur Miswak Herbal Toothpaste 100 ml

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Balto H.A., Al-Manei K.K., Bin-Mohareb T.M., Shakoor Z.A., Al-Hadlaq S.M. Cytotoxic effect of Salvadora persica extracts on human gingival fibroblast cells. Saudi Med. J. 2014; 35(8):810–815. [ PubMed] [ Google Scholar] The effects of BITC (a compound isolated from Salvadora persica root) on herpes simplex virus-1 (HSV-1) was investigated by Al-Bagieh et al. 44 The results of his plaque reduction essay indicated that BITC has a virucidal activity against HSV-1 at a concentration of 133 µg/ml. Thus, the authors supported the use of miswak ( Salvadora persica) as a preventive measure for controlling oral infections.Anticariogenic effects Following the use of miswak on various application for promoting oral health, evaluating its cytotoxicity effect against cells of the oral cavity is paramount. Balto et al. (2014) evaluated the safety of miswak oral irrigation solution, prepared using three different extraction method, namely ethanol, hexane and ethylacetate. The cell viability of human gingival fibroblast exposed to low (0.5mg/ml) and high (1mg/ml) concentration of miswak extract was evaluated using three different cell viability tests. The three assays used were 3-(4,5-Dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide, a tetrazole (MTS), lactic dehydrogenase (LDH), and crystal violet (CV) cell viability assay.

Mouthwash has been established to be an effective method for plaque reduction ( Farook and Said, 2018). Chlorhexidine, the cationic chemical agent commonly used in conventional mouthwash due to its potency against plaque, has been reported to cause many side effects such as teeth discoloration, oral mucosal irritation, and an unpleasant taste following its use ( Marion et al., 2013). Consequently, the search for natural alternative for mouthwash formulation was needed. It is often mentioned that the Islamic prophet Muhammad recommended the miswak's use. [11] He is quoted in various hadith extolling its virtues: [12] [13] Orthodontic chains are used by orthodontists to apply retraction forces to the teeth for orthodontic correction intervention. One concern about orthodontic chains, particularly the one made with elastomeric materials, is the force degradation that reduces its effectiveness overtime. The force degradation may be due to the exposure to the intraoral environment. Moreover, sodium bicarbonate, calcium, and chloride present in miswak make the tooth enamel stronger and assist in preventing cavities. 3.Whitens teeth Salvadorine and benzylisothiocyanate appear to be responsible for the antibacterial activity of Miswak. The plant also contains insoluble fluoride in high concentration, calcium, salicylic acid, and some antioxidants of unclear function. [8] Other considerations [ edit ]

After using the miswak for 5 days, trim it again with a knife or scissors and repeat the steps above. Ingredients in Miswak Restoration survival, from highest to lowest were miswak cement, chlorhexidine cement, and basic cement. Differences were significant at 6 and 9months. Mammad Z., Hsaine S., Djassinra T., Ounine K. The antibacterial and antioxidant effect of Salvadora persica on antibiotic resistant strains. Am. J. Plant Sci. 2018; 9(7):1478–1485. doi: 10.4236/ajps.2018.97108. [ CrossRef] [ Google Scholar] Miswak-incorporated toothpaste can be found prevalently in the market nowadays. In terms of plaque reduction, Gupta et al. (2012) in their triple-blind, parallel arm, RCT of 330 healthy children, compared the efficacy of miswak-incorporated toothpaste and fluoridated toothpaste. They found that significantly greater plaque reduction was achieved with the miswak-incorporated toothpaste compared to the conventional fluoridated toothpaste ( Gupta et al., 2012). Owens J., Sami W. The role of the Qur’an and Sunnah in oral health. J. Religion Health. 2016; 55(6):1954–1967. doi: 10.1007/s10943-015-0095-5. [ PubMed] [ CrossRef] [ Google Scholar]

Rezaei S., Rezaei K., Mahboubi M., Jarahzadeh M.H., Momeni E., Bagherinasab M., Targhi M.G., Memarzadeh M.R. Comparison the efficacy of herbal mouthwash with chlorhexidine on gingival index of intubated patients in Intensive Care Unit. J. Indian Soc. Periodontol. 2016; 20(4):404–408. doi: 10.4103/0972-124X.194269. [ PMC free article] [ PubMed] [ CrossRef] [ Google Scholar] Dabur Meswak is a scientifically formulated herbal toothpaste with pure extract of the Miswak tree, also known as ' Salvadore Persica', the famous ' Toothbrush Tree' used for centuries. The Miswak Tree gows slowly, resisting the brutal forces of nature amidst the sand dunes of Africa and South Asia. Even a small portion of this herb is capable of providing Complete Oral Care.

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The best thing is, it’s easy to use. Miswak doesn’t require the use of toothpaste. Here is a simple guide to help you. Step 1 Kassebaum, N.J., Smith, A.G., Bernabé, E., Fleming, T.D., Reynolds, A.E., Vos, T., Murray, C.J., Marcenes, W., GBD 2015 Oral Health Collaborators, 2017. Global, regional, and national prevalence, incidence, and disability-adjusted life years for oral conditions for 195 countries, 1990–2015: a systematic analysis for the global burden of diseases, injuries, and risk factors. J. Dent. Res. 96(4), 380-387. http://dx.doi.org/10.1177/0022034517693566. [ PMC free article] [ PubMed] Poor oral health has a major influence on the general quality of life and well-being ( Kassebaum et al., 2017). Several chronic and systemic diseases have been attributed to poor oral health. Diseases such as cardiovascular disease ( Kiswanjaya et al., 2017), stroke ( Shiraishi et al., 2018), mental illness ( Kisely et al., 2015), and diabetes ( Nakamura et al., 2016) have recently been associated with the consequences of poor oral health such as chronic oral infections, dental caries and periodontal disease. It is generally accepted that the oral hygiene maintenance through regular removal of dental plaque and food deposits is an essential factor in the prevention of poor oral health. Al-Bayaty, F.H., AI-Koubaisi, A.H., Ali, N.A.W. and Abdulla, M.A., 2010b. Effect of mouth wash extracted from Salvadora persica (Miswak) on dental plaque formation: a clinical trial. J Med Plant Res, 4(14), 1446-54.

Albabtain et al. (2017) investigated the cytotoxicity effect of miswak essential oil and chemical constituents of miswak including benzyl isothiocyanate (BITC), benzyl aldehyde, and benzyl cyanide in both gingival fibroblasts and oral keratinocytes. BITC at the concentration of less than 1µg/ml, miswak essential oil concentration of less than 1.4µg/ml, benzyl aldehyde concentration of less than 0.8µg/ml, and all concentration of benzyl cyanide demonstrated maintenance of the gingival fibroblast cell viability. In oral keratinocytes, viability was intact with 5 to 100µg/ml BITC and miswak essential oil with higher concentration improves its viability. The use of the miswak is frequently advocated in the hadith (the traditions relating to the life of Muhammad). Situations where the miswak is recommended to be used include before or during wudu (ablution), on waking up in the morning, before going to the mosque, before entering one's house, before and after going on a journey, on Fridays, [10] before sleeping and after waking up, when experiencing hunger or thirst and before entering any good gathering. [ citation needed] Dabur buys 3 Balsara group cos for Rs 143 cr". The Hindu. 28 January 2005 . Retrieved 13 March 2012. For ethanol extract, cell viability was maintained following exposure at both low and high concentration. For hexane extract, cell viability was maintained following exposure at low concentration while a slight cytotoxicity was detected with the high concentration. For ethyl acetate, slight cytotoxicity was detected with low concentration and maximum cytotoxicity was found with the high concentration. Taken together, cytotoxicity towards human gingival fibroblast were absent with miswak extracted with ethanol and hexane at low concentration, revealing its potential to be used as a safe oral irrigation solution.

After 3, 6, and 9months following restoration of damaged teeth with atraumatic restorative treatment (ART) with assigned GIC, the community periodontal index of treatment needs (CPITN) was measured. Many commercial toothpaste brands claim to make gums stronger, and it is their unique selling point. It is because the soft layer of tissue around your teeth, known as the gums, can reveal the condition of your dental health. Use the Miswaak, for verily, it purifies the mouth, and it is a Pleasure for the Lord. Jib-ra-eel (A.S.) exhorted me so much to use the Miswaak that I feared that its use would be decreed obligatory upon me and upon my Ummah. If I did not fear imposing hardship on my Ummah I would have made its use obligatory upon my people. Verily, I use the Miswaak so much that I fear the front part of my mouth being peeled (by constant and abundant brushing with the Miswaak) [15] Alternative forms [ edit ] Gupta P., Agarwal N., Anup N., Manujunath B.C., Bhalla A. Evaluating the anti-plaque efficacy of meswak (Salvadora persica) containing dentifrice: A triple blind controlled trial. J. Pharm. Bioallied Sci. 2012; 4(4):282. doi: 10.4103/0975-7406.103238. [ PMC free article] [ PubMed] [ CrossRef] [ Google Scholar] Ten percent water extraction of Salvadora persica is an effective antimicrobial agent when utilized clinically as an irrigant in the endodontic treatment of teeth with necrotic pulps. 35 Based on their in vitro study, Elangovan et al 36 revealed that aqueous extracts of neem ( Azadirachta indica) showed the greatest antimicrobial activity against Streptococcus mutans, while miswak ( Salvadora persica) extracts showed superior antimicrobial activity against Lactobacillus acidophilus. The constituent of Salvadora persica, such as N-benzyl-2-phenylacetamide, had shown moderate antimicrobial activity against Escherichia coli. The activity of the extracted N-benzyl-2-phenylacetamide from the miswak at a concentration of 87µg/mL was equivalent to 20µg/mL of gentamicin. 37 At 50% concentration, the miswak extract was effective in inhibiting Streptococcus mutans, Streptococcus sanguis, and Streprococus faecalis. At 5% and 10% concentrations, the extract was effective only against Streptococcus faecalis. It was concluded that miswak ( Salvadora persica) had an antibacterial effect at higher concentrations and that there was no difference in the antibacterial effects of fresh and one-month-old Miswak. 38 Almas and Stakiw 39 evaluated the effects of fresh and 18-year-old stored miswak ( Salvadora persica) at aqueous concentrations of 10% and 50% on 5 different microbes using a blood agar ditch method. After 48 hours of incubation at 4°C, it was found that all miswak extracts (at both 10% and 50%) had an antimicrobial effect against Streptococcus faecalis. However, only the 50% extract of fresh miswak had an inhibitory effect against Streptococcus mutans. AbdElRahman et al 40 assessed whether the crude extracts prepared from the roots and twigs of Salvadora persica inhibited the growth of some selected oral microbes ( Streptococcus mutans, Lactobacillus acidophilus, Actinobacillus actinomycetemcomitans, Actinomyces naeslundii, Porphyromonas gingivalis, Prevotella intermedia, Candida albicans). The author used sterile distilled water, 96% ethanol, 2% acetic acid, and ethyl acetate as solvents, and found that Streptococcus mutans was the most susceptible strain to all extracts, while Lactobacillus acidophilus was resistant to all extracts except for the root-ethanolic extract. Compared with the other solvents, the ethanolic extracts showed the strongest antimicrobial activity. Within the ethanolic extracts, the root extract was more potent than the twig extract. The stem-water extract was found to have the lowest potency. In the end, the author concluded that crude miswak extracts showed low to moderate antimicrobial activity compared with standard antimicrobial agents, such as 0.2% aqueous chlorhexidine and tea tree oil.

By making teeth plaque-free and bacteria-free, miswak aids in strengthening the gums as well. 5.Promotes fresh breath Make a regular practice of Miswak for verily it is the purification for the mouth and a means of the pleasure of the Lord. [14] Gurudath G., Vijayakumar K.V., Arun R. Oral hygiene practices: ancient historical review. J. Dent. Orofac. Res. 2012; 2(4):225–227. doi: 10.5005/jp-journals-10026-1047. [ CrossRef] [ Google Scholar] Studies indicate that Salvadora persica extract exhibits low antimicrobial activity compared to other oral disinfectants and anti-plaque agents like triclosan and chlorhexidine gluconate. [5] Al-Bayaty F.H., Zaidi W.I., Abdullah M.N., Emad O., Al-Obaidi M.M. Effect of Salvadora persica (Miswak) on alveolar bone healing after tooth extraction in rat. J. Int. Dent. Med. 2018; 11(3):770–777. [ Google Scholar]Sofrata A., Brito F., Al-Otaibi M., Gustafsson A. Short term clinical effect of active and inactive Salvadora persica miswak on dental plaque and gingivitis. J. Ethnopharmacol. 2011; 137(3):1130–1134. doi: 10.1016/j.jep.2011.07.034. [ PubMed] [ CrossRef] [ Google Scholar] The extract of the Salvadora persica stem possess anti-inflammatory activity. 76 Alali and Al-Lafi 77 recommended that the extract of Salvadora persica can be used effectively as a natural tool for tooth cleaning and as a natural analgesic for the treatment of toothaches.Efficacy of miswak as an oral hygiene tool