276°
Posted 20 hours ago

Hiplok Z LOK COMBO Multi-use Security Tie & Bike Lock

£9.175£18.35Clearance
ZTS2023's avatar
Shared by
ZTS2023
Joined in 2023
82
63

About this deal

Wu, Y. I. et al. A genetically encoded photoactivatable Rac controls the motility of living cells. Nature 461, 104–108 (2009). Oser, M. & Condeelis, J. The cofilin activity cycle in lamellipodia and invadopodia. J. Cell Biochem. 108, 1252–1262 (2009). Lai, F. P. L. et al. Arp2/3 complex interactions and actin network turnover in lamellipodia. EMBO J. 27, 982–992 (2008). Wang, H. & Hahn, K. M. LOVTRAP: a versatile method to control protein function with light. Curr. Protoc. Cell Biol. 73, 21.10.1–21.10.14 (2016).

Courtemanche, N., Pollard, T. D. & Chen, Q. Avoiding artefacts when counting polymerized actin in live cells with LifeAct fused to fluorescent proteins. Nat. Cell Biol. 18, 676–683 (2016). Wang, X., Chen, X. & Yang, Y. Spatiotemporal control of gene expression by a light-switchable transgene system. Nat. Methods 9, 266–269 (2012).

Zhou, X. X., Fan, L. Z., Li, P., Shen, K. & Lin, M. Z. Optical control of cell signaling by single-chain photoswitchable kinases. Science 355, 836–842 (2017). Haggarty, S. J., Koeller, K. M., Wong, J. C., Grozinger, C. M. & Schreiber, S. L. Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation. Proc. Natl Acad. Sci. USA 100, 4389–4394 (2003).

Hayashi-Takagi, A. et al. Labelling and optical erasure of synaptic memory traces in the motor cortex. Nature 525, 333–338 (2015). Leaver-Fay, A. et al. ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules. Meth. Enzymol. 487, 545–574 (2011). Ghosh, M. et al. Cofilin promotes actin polymerization and defines the direction of cell motility. Science 304, 743–746 (2004). Zoltowski, B. D., Vaccaro, B. & Crane, B. R. Mechanism-based tuning of a LOV domain photoreceptor. Nat. Chem. Biol. 5, 827–834 (2009). Yu, Y. & Lutz, S. Circular permutation: a different way to engineer enzyme structure and function. Trends Biotechnol. 29, 18–25 (2011).Beaty, B. T. et al. β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation. Mol. Biol. Cell 24, 1661–75, S1 (2013). This sort of 'just leaving it for five minutes' is where I feel the Hiplok Z Lok Combo is suitable. It's adequate to deter the casual thief from making off with your bike and gives a little more peace of mind that your flat white (me again) won't cost you a bike. There are three lengths, 100mm, 150mm and 200mm. The 150 length seems to be ideal during a 350 build, gives some room to still fit drivers above and below the gantry. Friedmann, D. R., Aguilar, A., Fan, J., Nachury, M. V. & Marmorstein, R. Structure of the α-tubulin acetyltransferase, αTAT1, and implications for tubulin-specific acetylation. Proc. Natl Acad. Sci. USA 109, 19655–19660 (2012). Li, T. et al. Incorporation of DDR2 clusters into collagen matrix via integrin-dependent posterior remnant tethering. Int. J. Biol. Sci. 14, 654–666 (2018).

Oser, M. et al. Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation. J. Cell Biol. 186, 571–587 (2009). Kawano, F., Aono, Y., Suzuki, H. & Sato, M. Fluorescence imaging-based high-throughput screening of fast- and slow-cycling LOV proteins. PLoS One 8, e82693 (2013). North, B. J., Marshall, B. L., Borra, M. T., Denu, J. M. & Verdin, E. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol. Cell 11, 437–444 (2003).User Access: Evaluate the options available for granting user access. Can you create virtual keys for family, friends, or service providers? Is there a temporary access feature for visitors? Eddy, R. J., Weidmann, M. D., Sharma, V. P. & Condeelis, J. S. Tumor cell invadopodia: invasive protrusions that orchestrate metastasis. Trends Cell Biol. 27, 595–607 (2017). Sharma, V. P. et al. Tks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cells. Curr. Biol. 23, 2079–2089 (2013). Chan, A. Y. et al. EGF stimulates an increase in actin nucleation and filament number at the leading edge of the lamellipod in mammary adenocarcinoma cells. J. Cell Sci. 111(Pt 2), 199–211 (1998).

Hughes, R. M. & Lawrence, D. S. Optogenetic engineering: light-directed cell motility. Angew. Chem. Int. Ed. Engl. 53, 10904–10907 (2014). Hodgson, L., Shen, F. & Hahn, K. Biosensors for characterizing the dynamics of rho family GTPases in living cells. Curr. Protoc. Cell Biol. Chapter 14, Unit 14.11.1–14.11.26 (2010). Suhre, K. & Sanejouand, Y.-H. ElNemo: a normal mode web server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Res. 32, W610–W614 (2004). Sidani, M. et al. Cofilin determines the migration behavior and turning frequency of metastatic cancer cells. J. Cell Biol. 179, 777–791 (2007).

Hiplok Z-Lok Security Ties

Pope, B. & Weeds, A. G. Binding of pig plasma gelsolin to F-actin and partial fractionation into calcium-dependent and calcium-independent forms. Eur. J. Biochem. 161, 85–93 (1986). Yi, J. J., Wang, H., Vilela, M., Danuser, G. & Hahn, K. M. Manipulation of endogenous kinase activity in living cells using photoswitchable inhibitory peptides. ACS Synth. Biol. 3, 788–795 (2014). Aizawa, H., Sutoh, K. & Yahara, I. Overexpression of cofilin stimulates bundling of actin filaments, membrane ruffling, and cell movement in dictyostelium. J. Cell Biol. 132, 335–344 (1996). Kuhlman, B., Jacobs, T. & Linskey, T. Computational design of protein linkers. Methods Mol. Biol. 1414, 341–351 (2016). Yang, N. et al. Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature 393, 809–812 (1998).

Asda Great Deal

Free UK shipping. 15 day free returns.
Community Updates
*So you can easily identify outgoing links on our site, we've marked them with an "*" symbol. Links on our site are monetised, but this never affects which deals get posted. Find more info in our FAQs and About Us page.
New Comment