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Documents" tab: Attachment of new document type "Handwritten amendments" possible under "Additional documents" screen PCT (PCT/RO/101 update April 2019) update 23 May 2019 available for (OLF) V5.11 (build 5.0.11.174 or lower)

medicines for depression or other mental health problems such as venlafaxine, quetiapine or diazepam The 1 January 2018 PCT/RO/101 release (version 3.51.256) is available in eOLF Client, incorporating the PCT-SAFE releases of April, July and October 2017. Ask your doctor about taking folic acid. Folic acid can lower the general risk of spina bifida and early miscarriage that exists with all pregnancies. However, it is unlikely that it will reduce the risk of birth defects associated with valproate use.Although there is no specific evidence of sudden recurrence of underlying symptoms following withdrawal of valproate, discontinuation should normally only be done under the supervision of a specialist in a gradual manner. This is due to the possibility of sudden alterations in plasma concentrations giving rise to a recurrence of symptoms. NICE has advised that generic switching of valproate preparations is not normally recommended due to the clinical implications of possible variations in plasma concentrations. EP1001: The reduction factor in "Fee Selection" is now kept when creating a draft by copying another EP1001 application

The asterisked (*) time periods are extendible by 2 months under r.108(2). A further 2 month extension is available under r.108(3) but it is unlikely that this will be requested. Document/Fee RequiredThis patch contains fee updates for PCT fees from 1 May 2013 and the addition of Welsh as a language of filing where GB is the receiving Office.