Joined in 2023 
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63 About this deal
Initially, I’m not certain I felt much of a difference. This being all new to me, I honestly don’t know what I should expect either. Comments that harass other posters will be deleted. Please be respectful toward other contributors. Comments containing language or concepts that could be deemed offensive will be deleted. Note this may include abusive, threatening, pornographic, offensive, misleading or libelous language. In a similar study, an elite cycling training center (Source Endurance) in Northern Colorado performed a placebo controlled, blinded, and randomized research study on the performance benefits of PR Lotion. A group of competitive cyclists rode at 140% of a predetermined 20 min time trial power for 30 seconds with 20 seconds of rest; then repeat the interval until exhaustion. They observed a 20% increase in the number of intervals completed before exhaustion when the cyclists used PR Lotion compared to applying a placebo control lotion.
BW holds equity in Momentous and has served as a scientific advisor to Momentous; BW stands to financially benefit from the success of Momentous’ products; BW has engaged in this research for and is publishing on behalf of Momentous. JH has received a research contract from Momentous; the University of Oregon remains Halliwill’s primary place of employment and all research are attributed to the University of Oregon. Taken together, our observations support the idea that transdermal bicarbonate delivery may impact pH buffering both intramuscularly and systemically. In contrast to the observed changes in pH, alterations in [Na +] and [K +] in both intramuscular dialysate and serum were less clear. With PR Lotion application, serum [Na +] was significantly elevated ( Table 2) and tended to decrease in the placebo condition. However, other changes in Na + and K + concentrations were either inconsistent or were observed during both the primary study and the placebo time control ( Table 2). 4.1 Bicarbonate loading I typically do two hard training rides (60-120 minutes) per week, plus a long ride on Saturday. These are the rides where I’ve been consistently using PR Lotion this year. (It isn’t needed for my recovery rides since the goal then is to not push myself hard.)
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The answer to this question is... well, yes and no. I've had three months to try to quantify the benefits and the answer is: some. Because of the reduced inflammation and muscle soreness between training sessions, PR Lotion can improve the rate of recovery or readiness to train. That is, diminished muscle soreness in the days following intense exercise, aids in the recovery of muscle function which can only enhance the quality of the subsequent training session. The improved readiness to train, combined with increased buffering potential in the muscle, promotes the maintenance of high training loads or high-quality training efforts. This means that the athlete is more ready and able to handle the required or prescribed training loads. PR Lotion can, therefore, help an athlete be more physically capable of performing the intended training session, which will allow for overall superior adaptations to the prescribed training.
Muscle activation is critically dependent upon the Na +/K + pump to re-establish resting ion gradients. An eventual dysregulation of gradients is thought to contribute to sensations of fatigue and a diminishment in muscle force production ( Sreter and Woo, 1963; Juel, 1986; Nielsen and Overgaard, 1996). Overgaard et al. ( Overgaard et al., 1999) highlighted the importance of assessing changes in both Na + and K + in combination rather than separately when resting gradients are lost in fatigue models. In the current study, the rise of Na + concentration in the blood and reduction in K + concentration in the intramuscular dialysate may suggest a shift to a greater amount of Na + located extracellularly with a greater amount of K + intracellularly. This could occur in response to an improvement in pH-sensitive Na +/K + pump kinetics where greater activity has been reported in a more alkaline environment ( Skou and Esmann, 1980). Similar reductions in K + concentrations observed in the placebo time control suggests changes may be in response to influences beyond alkalinization caused by PR Lotion, such as fluid compartment shifts or other factors, complicating our results. Nevertheless, alterations in the ion concentrations of Na + and K + are differentially expressed across these physiological mechanisms and between the conditions, warranting further investigation. 4.5 Challenges of microdialysis A less known, and less understood, benefit of bicarbonate or an enhanced buffering potential is improved recovery by reducing post-exercise or delayed onset muscle soreness (DOMS) following heavy exercise or training sessions. Pre-exercise application of PR Lotion can aid in recovery between training sessions in two ways. First, adequate bicarbonate levels in the muscle can reduce post-exercise inflammation. Bicarbonate creates an alkaline environment surrounding the muscle cells, which can reduce the chemical stress caused by acid production during intense exercise. This, in turn, can reduce the post-exercise inflammatory response following intense exercise [4]. It is this inflammatory response which, in part, contributes to DOMS experienced following a competition or intense training session. Second, PR Lotion may decrease edema or tissue swelling that occurs following heavy or long training sessions. Both sodium and bicarbonate concentrations in the extracellular space (and in the blood) can modulate fluid shifts between the inside and the outside of the muscle cells. It is the buildup of fluid or edema that contributes to the pain we sense as muscle soreness. Anything that can reduce the fluid accumulation in the muscle can reduce DOMS. I finished with a 4 minute jump rope Tabata and again, I was winded, but I didn’t have that same burning sensation in my muscles that I usually do. Consider me skeptically optimistic at this point. Early work by Costill et al., ( Costill et al., 1984), found that oral sodium bicarbonate could reduce metabolic acidosis in response to repeated bouts of supramaximal cycling and this was associated with improvements in cycling performance. Since then, the use of oral sodium bicarbonate as an ergogenic aid has produced mixed results due in part to differences in dosing practices, exercise models, acute ingestion versus chronic loading, and variation in gastrointestinal tolerance ( Carr et al., 2011; Calvo et al., 2021). Brad Wilkins. Ph.D. is VP of Science and Innovation at Amp Human and Chairman of Amp Human's Scientific Advisory Board. Dr. Wilkins has over 25 years of research experience with over 40 published scientific articles and patents. He received his Ph.D. from the University of Oregon and trained as a post-doctoral fellow at the Mayo Clinic. As an accomplished scientist at Nike, he founded the Nike+ Sport Performance Laboratory, and led the scientific team in Nike’s quest to break the two-hour marathon barrier (Breaking2). You can learn more about him and the rest of our Scientific Advisory Board members here.
Concentrations of K + and Na + were measured in dialysate and serum via flame photometry (BWB Technologies United States, Evans Mill, NY, United States) per manufacturer’s instructions. To eliminate intersample variance, all samples were thawed once and analyzed in the same run by a single technician. Sample results were inspected for visual stability across the sample run time and all samples with reported instability were re-processed. Sample results were recorded in millimolar (mM) concentrations in duplicate. 2.3 Statistical analysis
PR Lotion is the first and only topical lotion to deliver sodium bicarbonate directly through the skin. This enhances the buffering capacity of the body and the muscle while circumventing the potentially debilitating GI distress. In addition, PR Lotion removes much of the complexity required in pre-exercise ingestion protocol or strategies. In contrast to ingested sodium bicarbonate, there is little need for athletes to incorporate tedious pre-exercise protocols, strategies, or routines to combat negative side effects. This makes PR Lotion a very practical solution for delivering the performance benefits of sodium bicarbonate and a very scalable solution for athletes to use regularly during training and competition. PR Lotion effectively eliminates all problems associated with the ingestion of sodium bicarbonate, while providing athletes with the benefits described in over 40 years of sodium bicarbonate research. The results presented in the current work are presented clearly, honestly, and without fabrication, falsification, or inappropriate data manipulation. We would like to thank the subjects who cheerfully participated in this research study. Momentous provided the PR Lotion and placebo control lotion for this research. Conflict of interest Maughan, R.J., et al., IOC consensus statement: dietary supplements and the high-performance athlete. Br J Sports Med, 2018. 52(7): p. 439-455.As the sets progressed and the weights increased, I did notice something: I was breathing just as hard as ever, but my legs still felt primed for more. Call it a fluke. Call it a placebo. IDK, but the fatigue I would normally experience just wasn’t there, particularly in my calves. For decades, the bicarbonate buffering system has been a target of ergogenic supplements and interventions, primarily using oral loading of exogenous sodium bicarbonate in the hours to days preceding an intense exercise bout ( Galloway and Maughan, 1996; Marx et al., 2002; Carr et al., 2011; Calvo et al., 2021). While oral sodium bicarbonate loading increases blood pH and bicarbonate concentration and can result in improvements in exercise performance ( Hirche et al., 1975; Kesl and Engen, 1998), it has often been associated with performance encumbering gastric distress when consumed at “ergogenic” doses of 0.3g/kg to 0.5g/kg body weight ( Carr et al., 2011). Various strategies of oral loading have been employed to mitigate gastric distress, however, even when split doses are used deleterious side effects often persist ( Oliveira et al., 2017). In the short intensity series, blood lactate and pH were measured and compared 14 times. In the long intensity session, HR and RPE were each measured and compared five times. Each one of these time points is an opportunity to find a P value <0.05 or a significant difference between the treatment and placebo. As I’ve written before, when a study reports results of multiple outcomes and multiple exposures, it increases the probability that at least some of those results may be statistically significant even though there is no underlying effect. All study visits were held in the morning hours and subjects were asked to arrive to the laboratory wearing typical exercise clothing, shorts and a t-shirt, having abstained from food for the 2h preceding testing, caffeine for 6h, alcohol for 12h, and strenuous exercise for 24h. Upon arrival at the laboratory, a urine sample was collected to screen for pregnancy (if applicable). Subjects were instrumented in the supine position with an antecubital intravenous catheter for blood sampling, 3-lead electrocardiogram, and intramuscular microdialysis probe in the vastus lateralis for interstitial sampling. Once the probe was placed, 90min was allowed for resolution of placement trauma prior to collection of baseline samples for blood and dialysate. Room temperature remained thermoneutral (∼23°C) throughout the study.
Used by Tour de France winners, MTB World Champions, IronMan professionals and marathon world record holders It is well-known that sodium bicarbonate (baking soda) can boost performance in cyclists (here are articles from the US National Institute of Health and TrainingPeaks on the topic, but Google will bring up many more). The challenge with bicarb is the difficulty of ingestion: it is unpleasant to consume, and if you do it wrong things can go south fast. The TrainingPeaks article above says, “One of the more common side effects is gastrointestinal distress in the form of cramping, vomiting, and diarrhea.” So what is this magical lotion? It’s essentially nothing more than a topical delivery of sodium bicarbonate, more commonly referred to as baking soda. As it turns out, athletes have used baking soda for decades – it’s one of the most extensively studied ergogenic aids out there. But why would baking soda of all things improve performance?All studies were approved by the Institutional Review Board at the University of Oregon and were performed in accordance with the principles outlined by the Declaration of Helsinki. Written informed consent was obtained from all subjects after a verbal and written briefing of all experimental procedures. 2.2 Study design Personally, I think Amp Human's claims of 16 per cent more power and being able to complete 25 per cent more max high-intensity intervals is a little ambitious. What I can say is that while using it I seemed less susceptible to cramping during race simulation rides, and consistently produced more power at the end of races and identical turbo interval sessions. We're talking in the region of five per cent rather than the claimed figures, but perceptible and impressive nonetheless. Value and conclusion
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