Estro-Halt EU- Designed for Estrogen Support | Contains CDG, Indole-3-Carbinol & Apigenin

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Through an agreement between the European Union of Medical Specialists and the American Medical Association, physicians may convert EACCME® credits to an equivalent number of AMA PRA Category 1 Credits™. Information on the process to convert EACCME® credits to AMA credits can be found at www.ama-assn.org/education/earn-credit-participation-international-activities.

Ovarian preservation should be discussed with women in reproductive age with squamous cell carcinoma, can be considered in HPV-associated adenocarcinoma and is not recommended for HPV-independent adenocarcinomas. Opportunistic bilateral salpingectomy should be performed if ovaries are preserved. Ovarian transposition should be discussed upfront with the patient and individualized according to risk balance [IV, A]. Inclusion of patients with recurrent/metastatic disease in clinical trials is strongly recommended [V, A].

Measurements of tumor distance to all surgical margins (including minimum distance of uninvolved cervical stroma). Amanda Webster (UK), Ben Slotman (NL), Daan Nevens (BE), Ester Hammond (UK), Ina Schulz-Jurgenliemk (NL), Jens Overgaard (DK), Ludvig Muren (DK), Ludwig Van den Berghe (BE), Marianne Aznar (UK), Michael Baumann (DE), Michelle Leech (IE), Pierre Blanchard (FR) All data relevant to the study are included in the article or uploaded as supplementary information. to 5 years of relevant and proven experience in marketing and communications creating content to support organisational goals, preferably in a non-profit association of a scientific nature. The patient should be carefully counseled regarding treatment options, risks and consequences [V, A].

In patients with cervical advanced cancer, a multidisciplinary approach of physicians, nurses, psychologists, social workers, and community health workers is needed to manage psychosocial and spiritual suffering associated with social stigma deriving from genital disease, malodorous vaginal discharge, etc [IV, A]. Dykewicz CA (2001) Summary of the guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients. Clinical Infectious Diseases 33:139–44

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Platinum-based chemotherapy±bevacizumab is recommended for chemo-naïve, medically fit patients with recurrent/metastatic disease. Carboplatin/paclitaxel and cisplatin/paclitaxel are the preferred regimens [I, A].

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Image-guided adaptive brachytherapy (IGABT) (preferentially MRI) including access to intracavitary/interstitial techniques are needed to obtain a sufficiently high dose to ensure a high rate of local control in advanced cases with poor response to initial CTRT. This is especially important for non-squamous histology.Adjuvant treatment may be considered also if only isolated tumor cells are detected in SLN, although its prognostic impact remains uncertain [IV, C]. For patients with free surgical margins and in the absence of residual tumor on imaging (including non-suspicious LN), (chemo)radiotherapy is recommended as a treatment that avoids further surgical management [IV, B]. Imaging and laboratory tests should be performed only based on risk of recurrence, symptoms or findings suggestive of recurrence and/or side effects. With over 9 000 members in and outside Europe, ESTRO supports all the Radiation Oncology professionals in their daily practice: Radiation Oncologists, Medical Physicists, Radiobiologists and RTTs (Radiation Therapists) and the wider oncology community.