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The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete sexual intercourse). Its use is now one of the standard treatments for erectile dysfunction, including for males with diabetes mellitus. [19] Antidepressant-associated sexual dysfunction How to buy medicines safely from an online pharmacy. U.S. Food and Drug Administration. https://www.fda.gov/consumers/consumer-updates/how-buy-medicines-safely-online-pharmacy. Accessed Feb. 23, 2023.

It’s not known how long Viagra may last in females, because the drug isn’t approved for use in females. More studies are needed to know about Viagra use in females and how long it may last. Other forms of sildenafil (the active drug in Viagra) comes in other strengths, such as 20 mg. But Viagra only comes in the three strengths listed above. When to take Viagra Ciment J (November 1999). "Health situation in former communist bloc is dire, says Unicef". BMJ. 319 (7221): 1324. doi: 10.1136/bmj.319.7221.1324g. PMC 1174637. PMID 10567131. Give yourself time - You won’t instantly get an erection when taking Viagra, it can take 30-60 minutes to begin to feel the effect. You can take the tablet up to 4 hours before use.Viagra prescriptions almost triple in a decade". Pharmaceutical Journal. 21 August 2017 . Retrieved 8 October 2017. [ permanent dead link] Virectin says it works on various male sexual functions, including blood flow to the penis, boosting libido, and energy. This list does not contain all types of drugs that may interact with Viagra. Your doctor or pharmacist can tell you more about these interactions and any others that may occur with use of Viagra. Warnings Before you start taking Viagra, you should be aware of the symptoms of low blood pressure. If you have any of these symptoms, see your doctor. They’ll be able to determine how low your blood pressure is and whether it’s at a safe level.

You may have questions about Viagra and your treatment plan. It’s important to discuss all your concerns with your doctor. If you’re interested in knowing more about this, talk with your doctor. How long does Viagra last in women? Berenson A (4 December 2005). "Sales of Impotence Drugs Fall, Defying Expectations". The New York Times . Retrieved 20 August 2008. Some men also experience facial flushing, headaches, light headedness, nasal congestion, indigestion, palpitations (racing heartbeat), and blurred vision. For full information on side effects and correct use, see the patient information leaflet. Eloi-Stiven ML, Channaveeraiah N, Christos PJ, Finkel M, Reddy R (November 2007). "Does marijuana use play a role in the recreational use of sildenafil?". The Journal of Family Practice. 56 (11): E1-4. PMID 17976333.Milford, Phil (15 August 2011). "Pfizer Wins Viagra Patent Infringement Case Against Teva Pharmaceuticals". Bloomberg . Retrieved 1 April 2012. Your doctor won’t recommend your Viagra dosage by weight. But they may recommend a lower dose of the drug if you’re older than 65 years. This is because you may have an increased risk of side effects given your age. So, for example, the dosage for someone 70 years old may be 25 mg as needed, instead of 50 mg as needed. The molecular mechanism of smooth muscle relaxation involves the enzyme CGMP-dependent protein kinase, also known as PKG. This kinase is activated by cGMP and it phosphorylates multiple targets in the smooth muscle cells, namely myosin light chain phosphatase, RhoA, IP3 receptor, phospholipase C, and others. [50] Overall, this results in a decrease in intracellular calcium and desensitizing proteins to the effects of calcium, engendering smooth muscle relaxation. [50]