Solgar Inositol 500 mg Vegetable Capsules - Vitamin B8 - Vegan, Vegetarian, Kosher, 50 Count (Pack of 1)

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Ovasitol by Theralogix is the market-leading inositol supplement for women with PCOS. And for good reason. Ovasitol contains myo-inositol and D-chiro-inositol in a 40:1 ratio. As described above, this is the most effective formulation for the treatment of PCOS.

M. and E. Proietti, The combined therapy with myo-inositol and D-chiro-inositol reduces the risk of metabolic disease in PCOS overweight patients compared to myo-inositol supplementation alone. Eur Rev Med Pharmacol Sci, 2012. 16(5): p. 575-81. Phytic acid is the main source of dietary inositol. Some of the best high-inositol foods for women with PCOS include [ 7]: Papaleo E, Unfer V et al. Myo-inositol in patients with polycystic ovary syndrome: a novel method for ovulation induction. Gynecol Endocrinol. 2007 Dec;23(12):700-3. Epub 2007 Oct 10. Su XB, Ko AA, Saiardi A Regulations of myo-inositol homeostasis: Mechanisms, implications, and perspectives. Adv Biol Regul. (2023-Jan) Unfer V, Facchinetti F, Orrù B, Giordani B, Nestler J Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials Endocr Connect. (2017 Nov)Hashemi Tari S, Sohouli MH, Lari A, Fatahi S, Rahideh ST. The effect of inositol supplementation on blood pressure: A systematic review and meta-analysis of randomized-controlled trials. Clin Nutr ESPEN 2021;44:78-84. View abstract. There are also not enough studies to determine the safety of the supplements while breastfeeding. However, breast milk seems to be naturally rich in inositol ( 39). Jamilian H, Jamilian M et al. Comparison of myo-inositol and metformin on mental health parameters and biomarkers of oxidative stress in women with polycystic ovary syndrome: a randomised, double-blind, placebo-controlled trial. J Psychosom Obstet Gynaecol. 2018 Dec; 39(4): 307-314 R.Z., et al., Risk factors of vitamin B(12) deficiency in patients receiving metformin. Arch Intern Med, 2006. 166(18): p. 1975-9. These studies have typically used doses of 2–4 grams per day, and benefits have been seen in normal-weight, overweight and obese women.

Schizophrenia symptoms - Levine J, Goldberger I, Rapaport A, Schwartz M, Schield C, Elizur A, Belmaker RH, Shapiro J, Agam G CSF inositol in schizophrenia and high-dose inositol treatment of schizophrenia Eur Neuropsychopharmacol. (1994 Dec) Amazingly, 20% of the women taking inositol supplements no longer met the criteria for metabolic syndrome by the end of the study ( 24). Summary E., P. Rizzo, and V. Benedetto, Insulin sensitiser agents alone and in co-treatment with r-FSH for ovulation induction in PCOS women. Gynecol Endocrinol, 2010. 26(4): p. 275-80. Carlomagno & Unfer (2011), Inositol safety: clinical evidences. Eur Rev Med Pharmacol Sci, 15: 931-936 D-chiro-inositol alone should be approached more cautiously. High dosages may adversely affect egg quality [ 61].

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J.E., et al., Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome. N Engl J Med, 1999. 340(17): p. 1314-20. For example, an early study demonstrated that taking a 12-gram inositol supplement every day for 4 weeks improved symptoms in people with depression ( 10).

Weight - Santamaria A, Giordano D, Corrado F, Pintaudi B, Interdonato ML, Vieste GD, Benedetto AD, D'Anna R One-year effects of myo-inositol supplementation in postmenopausal women with metabolic syndrome Climacteric. (2012 Oct)Fertility - Ciotta L, Stracquadanio M, Pagano I, Carbonaro A, Palumbo M, Gulino F Effects of myo-inositol supplementation on oocyte's quality in PCOS patients: a double blind trial Eur Rev Med Pharmacol Sci. (2011 May) Kachhawa G, Senthil Kumar KV, Kulshrestha V, Khadgawat R, Mahey R, Bhatla N. Efficacy of myo-inositol and d-chiro-inositol combination on menstrual cycle regulation and improving insulin resistance in young women with polycystic ovary syndrome: A randomized open-label study. Int J Gynaecol Obstet 2021. View abstract.