Girls Frozen Socks - Pack of 2

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Cooling was achieved using a thermoregulator device to supply water cooled to 22°C to a limb-cooling wrap applied at the lower leg and foot. This consideration is discussed further in the next section on implications for practice and further study. Patient Neurotoxicity Questionnaire results: significantly lower grades of peripheral neuropathy in the intervention side ( p< . Larger, randomized controlled trials are needed to better understand the impact of peripheral cooling on CIPN.

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The authors reported a significantly lower incidence of ≥ grade 2 peripheral neuropathy in the intervention group (5. To date, interventions to effectively prevent this toxicity have not been established, and interventions to treat CIPN have produced only modest results.

Variations in patient characteristics, drug regimens used, and outcome measures are also significant limitations.

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Additional studies are needed to further assess the validity of the findings in the Tsuyuki study and to discern benefit from compression compared with direct cooling. Factors influencing the effectiveness of scalp cooling in the prevention of chemotherapy-induced alopecia.Evaluation of prevention interventions for taxane-induced dermatologic adverse events: A systematic review. In addition to results related to CIPN severity, this study also reported beneficial results of the intervention related to CIPN incidence, including decreased impairments in hand tactile sensitivity (27.