Schwabe Kaloba Pelargonium Cough and Cold Relief Tablets, 30 g

Product Information

Since Kaloba syrup is a natural product, slight variations in colour and taste may occur. 6.4 Special precautions for storage Anti-bacterial: The herb extract prevents bacteria from attaching to cells in your mucous membranes.

There were no significant differences between mucolytics and placebo for the outcomes of productive cough and expectoration at end of treatment (at 7 days), pulmonary function at day 3, febrile state at 6 days, dyspnoea at 6 to 7 days, bad general condition after 6 to 7 days, and appetite trouble (not defined) at the end of treatment (5 to 9 days) in children with acute upper and lower respiratory tract infection (very low quality evidence). There was also no significant difference for the outcome of abnormal chest signs (for example wheezing or rattling) after 5 days, but there was a significant difference for this outcome at the end of treatment (28 days; 2% versus 16%; very low quality evidence). A study involving 105 people with bacterial sinusitis, in which symptoms had been present for at least one week, showed that taking Pelargonium extracts three times daily for up to 22 days produced significant improvements in symptoms, with faster recovery than those taking placebo, and no significant side effects. Pelargonium and tonsillitis In rare cases (≥ 1/10,000 to ≤ 1/1,000) mild bleeding from the gums or nose may occur. Furthermore, hypersensitivity reactions (e.g. exanthema, urticaria, pruritus of skin and mucous membranes) have been described in rare cases. Such reactions may occur after the first intake of the product.Based on evidence and experience, the committee agreed that an immediate antibiotic prescription should be offered to people (adults or children) with an acute cough (associated with an upper respiratory tract infection or acute bronchitis) who are identified as systemically very unwell (ideally at a face-to-face clinical examination), because these people require prompt treatment with an antibiotic. Boldy DA, Skidmore SJ, Ayres JG. Acute bronchitis in the community: clinical features, infective factors, changes in pulmonary function and bronchial reactivity to histamine. Respir Med. 1990;84(5):377-385.

Schroeder K, Fahey T. Over-the-counter medications for acute cough in children and adults in ambulatory settings. Cochrane Database Syst Rev. 2004;4:CD001831. Antibiotics did not improve the overall clinical condition of people with acute bronchitis, or the number of people with improvement at physician follow-up. Antibiotics did improve abnormal lung examination at follow‑up, but the committee agreed this was not an important patient-orientated outcome for people with acute bronchitis, and this outcome was heavily influenced by 1 study of cefuroxime. There was no evidence directly comparing different antibiotics. However, subgroup analysis from a systematic review in people with acute bronchitis did find some differences between antibiotics compared with placebo. If the symptoms persist during the use of the medicinal product, a doctor or a qualified health care practitioner should be consulted. 4.3 Contraindications Experience in Germany suggests that Pelargonium sidoides extracts are safe, with 1 in 189,000 patients experiencing a side effect during an average treatment period of 10 days. A few reports of potential liver problems were found to relate to other causes.The committee agreed that the evidence for inhaled corticosteroids was mixed. There was some evidence that it reduced cough symptoms in adults with an acute or subacute cough (particularly in non-smokers) but other evidence that it had no effect. No evidence for oral corticosteroids was found. Chuchalin AG, Berman B, Lehmacher W. Treatment of acute bronchitis in adults with a pelargonium sidoides preparation (EPs 7630): a randomized, double-blind, placebo-controlled trial. Explore (NY). 2005;1(6):437-445. Gastro-intestinal complaints such as stomach pain, heartburn, nausea or diarrhoea may occur uncommonly (≥ 1/1,000 to < 1/100) during treatment with Kaloba. The committee discussed the evidence that inhaled corticosteroids reduced additional treatments being sought, and they could reduce the prescribing of antibiotics for acute cough. However, any prescribed alternatives to antibiotics have workload implications as people are likely to re‑consult and expect similar treatments in the future, sending the wrong message that prescribed treatment is needed for a largely self‑limiting condition. Tell your doctor or pharmacist if any of the above side-effects becomes serious or if you notice any other side-effects not listed above. Reporting of side effects