Little Live Pets 28847 Cozy DOZYS, Multi-Colour

Product Information

M. Sharma, G. Janssen, J. Leggett, A. P. Kentgens and P. J. van Bentum, J. Magn. Reson., 2015, 258, 40 CrossRef CAS PubMed . E. Persch, O. Dumele and F. Diederich, Angew. Chem., Int. Ed., 2015, 54, 3290–3327 CrossRef CAS PubMed.

S. Korchak, L. Kaltschnee, R. Dervisoglu, L. Andreas, C. Griesinger and S. Gloggler, Angew. Chem., Int. Ed., 2021, 60, 20984 CrossRef CAS PubMed . M. Lucarini, B. Luppi, G. F. Pedulli and B. P. Roberts, Chem. – Eur. J., 1999, 5, 2048–2054 CrossRef CAS. Fig. 7 Ultrafast NMR spectra of a mixture of 7 metabolites in H 2O/D 2O (90/10): (a) DQS (c) COSY. All spectra were recorded in four interleaved scans to increase the observable spectral width, and four dummy scans resulting in an acquisition time of 41 s, using a double-quantum build-up delay τ = 25 ms. Spectrum (b) was obtained from spectrum (a) by a shearing transformation at a processing stage. All spectra were recorded with a 600 MHz spectrometer equipped with a cryogenic probe. Reproduced from ref. 156 with permission from the Royal Society of Chemistry.

2D NOESY

Small-angle neutron and X-ray scattering Techniques Small-angle scattering techniques are powerful methods to investigate structures of supramolecular assemblies in solution or of soft matter, e.g. gels. Neutron (SANS) and X-ray scattering (SAXS) often require that samples are transported to specialist beam lines, although for example SAXS is increasingly available also as a lab-based technique.

After discussing the most relevant techniques for the structural characterisation of supramolecular molecules, we move to present three examples where supramolecular systems were successfully characterised by multi-technique approaches. In particular, we highlight the powerful interplay of the already discussed techniques while also mentioning the impact of other methods. 7 Host–guest complex formation of pyridine[4]arenes Molecular recognition describes the specific binding between two molecules via non-covalent interactions, for example between a host and a guest molecule. 80,81 This concept represents a major challenge in supramolecular chemistry because it is particularly important for catalytic processes and molecular sensors. In this context, binding preferences of macrocycles towards cationic, neutral or anionic guests are a critical aspect of fundamental supramolecular research. J. N. Thomas, V. Ramaswamy, I. M. Litvak, T. L. Johnston, A. S. Edison and W. W. Brey, IEEE Trans. Appl. Supercond., 2021, 31, 20210222 Search PubMed . A. Fernandez, J. Ferrando-Soria, E. M. Pineda, F. Tuna, I. J. Vitorica-Yrezabal, C. Knappke, J. Ujma, C. A. Muryn, G. A. Timco, P. E. Barran, A. Ardavan and R. E. P. Winpenny, Nat. Commun., 2016, 7, 1–6 Search PubMed. J. Ferrando-Soria, A. Fernandez, D. Asthana, S. Nawaz, I. J. Vitorica-Yrezabal, G. F. S. Whitehead, C. A. Muryn, F. Tuna, G. A. Timco, N. D. Burton and R. E. P. Winpenny, Nat. Commun., 2019, 10, 1–7 CrossRef CAS PubMed.B. Schade, A. K. Singh, V. Wycisk, J. L. Cuellar-Camacho, H. von Berlepsch, R. Haag and C. Böttcher, Chem. – Eur. J., 2020, 26, 6919–6934 CrossRef CAS PubMed. F. Zhang, S. L. Robinette, L. Bruschweiler-Li and R. Bruschweiler, Magn. Reson. Chem., 2009, 47(suppl 1), S118 CrossRef CAS PubMed . To investigate the properties of this system further, picric acid was applied as a proton source, to remove the anion from the oligomer after protonation. This was intended to lead to longer chains, which was confirmed by lower diffusion coefficients in the DOSY experiment. Furthermore, the diffusion coefficient of the picrate anion was higher than in free solution, which suggested a loose attachment to the oligomer. J. Farjon, C. Milande, E. Martineau, S. Akoka and P. Giraudeau, Anal. Chem., 2018, 90, 1845 CrossRef CAS PubMed . N. Eshuis, R. L. E. G. Aspers, B. J. A. van Weerdenburg, M. C. Feiters, F. P. J. T. Rutjes, S. S. Wijmenga and M. Tessari, Angew. Chem., Int. Ed., 2015, 54, 14527 CrossRef CAS PubMed .